Epson EcoTank Pro ET-16650: Setup, Drivers, Ink and Common Problems

Is the Epson EcoTank Pro ET-16650 right for you?

The ET-16650 adds PCL 5/6 and PostScript 3 to the ET-16600 platform, which is what architects, engineering firms and managed offices need when printing from CAD software, print servers or Linux. Everything else matches the ET-16600: 25 ppm pigment printing, an A3 duplex ADF and a replaceable maintenance box. The extra cost is only justified if you need those page description languages, so home crafters should buy the ET-16600 or ET-15000 instead.

Best for: Design and engineering offices needing A3 with PostScript or PCL

Setting up the Epson EcoTank Pro ET-16650

Install the PostScript or PCL driver from epson.com/support on managed networks, or the Universal Print Driver for Windows fleets. Lock down Web Config with an admin password and assign a static IP over Ethernet. The touchscreen wizard and Smart Panel remain available for Wi-Fi setup on either band.

1. Unbox and prepare. Remove every piece of shipping tape and packing material, install the ink bottles (fill each tank to the upper line), and load paper in the tray.
2. Join your Wi-Fi. Keep the printer close to the router for setup. Most printers only connect to the 2.4GHz band, so if your router broadcasts one merged network name you may need to split the bands temporarily. See our Wi-Fi guide if it will not join.
3. Install the setup app. Use Epson's official app rather than a driver you found on a search result — third-party driver sites are the most common source of printer malware.
4. Add the printer. On Windows 11: Settings › Bluetooth & devices › Printers & scanners › Add device. On macOS: System Settings › Printers & Scanners › Add Printer.
5. Print a test page and run a scan if this is an all-in-one, so you find any problem now rather than when you are in a hurry.

Ink, toner and supplies

The Epson EcoTank Pro ET-16650 uses the following consumables. Match the number exactly when you buy: the same printer family often uses several different cartridge numbers by region.

• Epson 542 Black (US)
• Epson 113 Black (UK/EU)
• Epson 542/113 Cyan/Magenta/Yellow ink bottles
• Epson C9345 maintenance box

High-yield (XL) versions almost always cost less per page if you print regularly. On third-party ink and toner, read our honest assessment first, and note that some manufacturers push firmware that rejects non-original chips.

Full specifications